*Evidence-Based Medicine = completion of a level 1 prospective, placebo-controlled, randomized (1:1), double-blinded, multi-centered clinical study
** No peer-reviewed publications signifies that a general search at http://www.ahsl.arizona.edu.ezproxy1.library.arizona.edu/ebmsearch/CollegeofMedicine/ using the device name and/or company name did not prod
*** Prior to the development of the Zerona device, Zerona-like device produced by the same manufacturer of Zerona (Erchonia Medical) assessed laser's effect on fat tissue. The parameter of laser that has been shown to modulate the fat cell is 635nm between 5 and 20mW. Competitors using the wrong output parameters continuously cite Dr. Neira' s work using the Zerona parameters.
**** Caruso-Davis M, et al. The efficacy of the Lapex2000 lipolaser in body contouring and fat reduction. Obesity. 2007;15:A99. Although it says Obesity Journal, a search on the Obesity Journal website cannot loc
 Friedman et al. The use of hybrid radiofrequency device for the treatment of rhytides and lax skin. Dermatol Surg. 2007;33(5):543-51.
 de Pino E, et al. Effect of controlled volumetric tissue heating with radiofrequency on cellulite and the subcutaneous tissue of the buttock and thighs
 Braun M. Combination of a new radiofrequency device and blue light for the treatment of acne vulgaris. J Drugs Dermatol. 2007;6(8):838-40
 Atiyeh BS, Dibo SA. Nonsurgical nonablative treatment of aging skin: radiofrequency technologies between aggressive marketing and evidence-based efficacy. Aesthetic Plast Surg. 2009;33(3):283-94
 Elsaie ML, et al. Nonablative radiofrequency for skin rejuvenation. Dermatol Surg. 2010;36(5)577-89.
 Fatemi A. High-intensity focused ultrasound effectively reduces adipose tissue. Semin Cutan Med Surg. 2009;28(4):257-62.
 Gadsden E, et al. Evaluation of a novel high-intensity focused ultrasound device for ablating subcutaneous adipose tissue for noninvasive body contouring: safety studies in human volunteers. Aesthet Surg J. 2011;31
 Jewell ML, et al. Evaluation of a novel high-intensity focused ultrasound device: preclinical studies in a porcine model. Aesthet Surg J. 2011;31(4):429-34.
 Kulick MI. Evaluation of a non-invasive, dual-wavelength laser-suction and massage device for the regional treatment of cellulite. Plast Reconstr Surg. 2010;125(6):1788-96.
 Lach E. Reduction of subcutaneous fat and improvement in cellulite appearance by dual-wavelength, low-level laser energy combined with vacuum massage. J Cosmet Laser Ther. 2008;10(4):202-9.
 Anolik R, et al. Radiofrequency devices for body shaping: a review and study of 12 patients. Semin Cutan Med Surg. 2009;28(4):236-43.
 Brightman L, et al. Improvement in arm and post-partun abdominal and flank subcutaneous fat deposits and skin laxity using a bipolar radiofrequency, infrared, vacuum and mechanical massage device. Lasers Surg M
 Nelson AA, et al. Cryolipolysis for reduction of excess adipose tissue. Semin Cutan Med Surg. 2009;28(4):244-9
 Klein KB, et al. Non-invasive Cryolipolysis for subcutaneous fat reduction does not affect serum lipid levels or liver function tests. Lasers Surg Med. 2009;41(10):785-90.
 Avram MM, Harry RS. Cryolipolysis for subcutaneous fat layer reduction. Lasers Surg Med. 2009:41(10):703-8.
 Dover J, et al. A prospective clinical study of non-invasive Cryolipolysis for subcutaneous fat layer reduction-Interim Report of Available Subject Data. Laser Surg Med. 2009;S21:45.
 Coleman SR, et al. Clinical efficacy of noninvasive Cryolipolysis and its effects on peripheral nerves. Aesthetic Plast Surg. 2009;33(4):482-8.
 Neira R, et al. Effects of the electric laser diode beam on in vitro human adipose tissue culture. Congreso Bolivariano de Cirugia Plastica Reconstructive. 2001
 Neira R, et al. Fat liquefaction: Effect of low level laser energy on adipose tissue. Plast Reconstr Surg. 2002;110:912-922
 Neira R, et al. In vitro culture of adipose cells after irradiating them with a low level laser device. Congresso Bolivariano de Cirugia Plastica Reconstructiva. 2001
 Neira R, et al. Fat liquefication: effect from low level laser energy. Presented at the Society of Latin American Plastic Surgeons Meeting; Orlando, Fl.; Nov.5, 2001
 Ramirez-Montanan A, et al. Changes on human fat cell's architecture after low-level laser exposure. Paper presented at: 34th National Congress of Mexican Plastic and Aesthetic and Reconstructive Surgery Associat
 Neira R, Jackson R, et al. Low-level laser assisted lipoplasty: Appearance of fat demonstrated by MRI on abdominal tissue. Am J Cosmet Surg. 2001;18(3):133-40.
 Maloney R. Body Contouring with a multiple diode laser system. Lasers Surg Med. 2008;S21:179.
 Jackson R, et al. Low level laser therapy as a non-invasive approach for body contouring: A randomized, controlled study. Lasers Surg Med. 2009;31:799-809